Figure 6.

Effects of Stevia extracts on glucose transport activity compared to the effect of insulin. SH-SY5Y (a) and HL-60 (b) cells were treated with steviol glycosides (1 mg/mL), with 100 nM insulin (I), with steviol glycosides and insulin simultaneously, or 1 mM standard compounds (StReb, StStev). Glucose uptake was assayed as described in Section 2. Results are expressed as means ± SD of three independent experiments, each performed in triplicate. Statistical analysis was performed by Bonferroni multiple comparison test following one-way ANOVA. *P < 0.05, significantly different from control cells; °P < 0.05 significantly different from the corresponding cells not stimulated with insulin.