Table 2.
PFT results by HIV status
| PFT results | HIV+ | HIV− | p-value |
|---|---|---|---|
| FEV1 in L, pre-BD, mean (SD) | 3.16 (0.8) | 3.23 (0.8) | 0.4 |
| FEV1, %predicted pre-BD, mean (SD) | 90 (19) | 91 (19) | 0.5 |
| FEV1 in L, post-BD, mean (SD) | 3.31 (0.8) | 3.39 (0.8) | 0.3 |
| FEV1, %predicted post-BD, mean | 95 (19) | 96 (19) | 0.4 |
| FVC in L, pre-BD, mean (SD) | 4.28 (0.9) | 4.35 (0.9) | 0.6 |
| FVC, %predicted pre-BD, mean (SD) | 95 (16) | 96 (18) | 0.9 |
| FVC in L, post-BD, mean (SD) | 4.34 (0.9) | 4.39 (0.9) | 0.7 |
| FVC, %predicted post-BD, mean (SD) | 97 (15) | 97 (16) | 0.9 |
| FEV1/FVC post-BD, mean (SD) | 0.76 (0.1) | 0.78 (0.1) | 0.4 |
| FEV1/FVC<0.70 | 18% | 16% | 0.5 |
| Bronchodilator responsiveness* | 16% | 13% | 0.2 |
| Raw DLCO, mean (SD) | 21.9 (6.2) | 23.9 (6.3) | 0.001 |
| DLCO**, %predicted, mean (SD) | 69 (19) | 76 (18) | <0.001 |
| DLCO ≤60% predicted, n% | 30% | 18% | <0.001 |
BD = Bronchodilator; DLCO = diffusing capacity of the lung for carbon monoxide; FEV1 = forced expiratory volume in one second; FVC = forced vital capacity; SD = standard deviation
*
Bronchodilator responsiveness was present if the FEV1 and/or FVC increased by at least 12% and 200 mL following bronchodilator administration.
**
Percent predicted DLCO values are corrected for hemoglobin.