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. Author manuscript; available in PMC: 2013 Dec 2.

Published in final edited form as: Chem Res Toxicol. 2009 Jul;22(7):10.1021/tx900127s. doi: 10.1021/tx900127s

Effects of flavone and nine flavonoids, pyrene, phenanthrene, naphthalene, ANF and BNF on EROD activities catalyzed by P450 1A1 ( ), P450 1A2 (shaded column, ), and P450 1B1 (■). The data presented are mean IC₅₀ values (n=3) and the standard deviations in these cases were less than 15% of the values. Control activities for EROD by P450 1A1, 1A2, and 1B1 were 45 ± 5, 6.5 ± 0.8, and 26 ± 4 nmol/min/nmol P450, respectively.

Inline graphic — Effects of flavone and nine flavonoids, pyrene, phenanthrene, naphthalene, ANF and BNF on EROD activities catalyzed by P450 1A1 ( ), P450 1A2 (shaded column, ), and P450 1B1 (■). The data presented are mean IC₅₀ values (n=3) and the standard deviations in these cases were less than 15% of the values. Control activities for EROD by P450 1A1, 1A2, and 1B1 were 45 ± 5, 6.5 ± 0.8, and 26 ± 4 nmol/min/nmol P450, respectively.