Table 1. Effect of MPC on Membrane bound enzymes in the liver of control and experimental animals.
Treatment | Na+/K+ ATPase | Mg2+ ATPase | Ca2+ ATPase |
Group 1 (Control) | 4.16 ± 0.32 | 12.8 ± 0.23 | 7.5 ± 0.54 |
Group 2 (Tumor bearing animals) | 2.35 ± 0.24 a | 6.9 ± 0.48 a | 3.06 ± 0.21 a |
Group 3 (MPC 200 mg/kg) | 2.79 ± 0.25 b | 7.8 ± 0.84 a | 4.03 ± 0.33 a |
Group 4 (MPC 400 mg/kg) | 3.32 ± 0.16 d | 9.2 ± 0.56 b | 5.52 ± 0.19 b, e |
N=6 animals in each group; each value is expressed as mean ± SEM
aP<0.001; bP<0.01; Vs Control
dP<0.05; eP<0.001 Vs Cancer bearing animals
Units: µmoles of Pi liberated/min/mg protein.
Data were analysed by one way ANOVA followed by Tukey Kramer multiple comparison test.