Table 1. Histopathology scoring of liver tissue for rats supplemented with different doses of Nigella sativa supplementation for 28 days.
Doses (g/kg) of Nigella sativa |
0.0 | 0.01 | 0.1 | 1 |
Score | 0 1 2 3 4 | 0 1 2 3 4 | 0 1 2 3 4 | 0 1 2 3 4 |
Hepatic vacuolization | 6 0 0 0 0 | 6 0 0 0 0 | 6 0 0 0 0 | 6 0 0 0 0 |
Hepatic degeneration | 6 0 0 0 0 | 6 0 0 0 0 | 6 0 0 0 0 | 6 0 0 0 0 |
Hepatic inflammation | 6 0 0 0 0 | 6 0 0 0 0 | 6 0 0 0 0 | 6 0 0 0 0 |
Necrosis | 6 0 0 0 0 | 6 0 0 0 0 | 6 0 0 0 0 | 6 0 0 0 0 |
Fatty degeneration | 0 0 0 0 0 | 0 5 1 0 0 | 0 5 1 0 0 | 0 2 4 0 0 |