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. 2013 Feb 7;3(1):13–18. doi: 10.5681/apb.2013.003

Table 1. Evaluation of analgesic activity by acetic acid induced writhing method.

Sr. No. Treatment Dose mg/kg Writhing episodes in 15 min (Mean ± S.E.M.) Percent protection
1 Control -- 38.70±0.5547 -
2 Ibuprofen 10 13.19±0.6921** 66
3 IIIa 50 17.28±0.6647** 55
4 IIIb 50 18.24±0.6425** 53
5 IIIc 50 24.89±0.5354** 36
6 IIId 50 15.65±0.7845** 60
7 IIIe 50 26.45±0.8121** 32
8 IIIf 50 16.46±0.5744** 57
9 IIIg 50 27.65±0.5478** 29
10 IIIh 50 18.57±0.4545** 52
11 IIIi 50 16.49±0.6545** 57
12 IIIj 50 16.47±0.2254** 57
13 IVa 50 16.45±0.5456** 57
14 IVb 50 17.49±0.5641** 55
15 IVc 50 21.73±0.5974** 44
16 IVd 50 15.44±0.6133** 60
17 IVe 50 22.45±0.5525** 42
18 IVf 50 15.36±0.6455** 60
19 IVg 50 19.65±0.7322** 49
20 IVh 50 17.22±0.4855** 56
21 IVi 50 19.47±0.6513** 50
22 IVj 50 14.24±0.4745** 63
23 IV3a 100 15.44±0.4454** 60
24 IV3b 100 22.65±0.5546** 42
25 IV3c 100 19.47±0.5941** 50
26 IV3d 100 21.77±0.4423** 44
27 IV3e 100 25.49±0.4473** 34
28 IV3f 100 19.42±0.6651** 50
29 IV3g 100 26.56±0.4329** 31
30 IV3h 100 28.56±0.7325** 26
31 IV3i 100 23.58±0.6423** 39
32 IV3j 100 19.26±0.4523** 50
33 Ih 25 20.54±0.6425** 47
34 Ii 25 22.89±0.5214** 41
35 Ij 25 18.34±0.4527** 53
36 IIh 25 20.57±0.8592** 47
37 IIi 25 22.44±0.6854** 42
38 IIj 25 15.47±0.8957** 60
** P < 0.01 represent significant difference when compared with control groups.