Table 4.
The correlation of V-ATPase expression with drug sensitivity (resistance) in squamous cell lung cancer
| V-ATPase |
Cyclophosphamide |
Gemcitabine |
Doxorubicin |
Paclitaxel |
Cisplatin |
||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| R | LS | MS | HS | p value | R | LS | MS | HS | p value | R | LS | MS | HS | p value | R | LS | MS | HS | p value | R | LS | MS | HS | p value | |
| _ |
0 |
3 |
2 |
2 |
χ2 =30.12 |
0 |
2 |
3 |
2 |
χ2 = 24.143 |
0 |
2 |
0 |
5 |
χ2 = 34.11 |
0 |
0 |
0 |
0 |
χ2 = 10.03 |
0 |
0 |
2 |
5 |
χ2 = 32.88 |
| + |
4 |
7 |
2 |
0 |
p = 0.00 |
3 |
6 |
4 |
0 |
p = 0.000 |
0 |
4 |
5 |
1 |
p = 0.000 |
0 |
1 |
5 |
7 |
p = 0.124 |
3 |
3 |
6 |
1 |
p = 0.000 |
| ++ | 20 | 3 | 0 | 0 | rs = −0.742 | 12 | 11 | 0 | 0 | rs = −0.607 | 0 | 9 | 1 | 0 | rs = −0.630 | 4 | 3 | 5 | 11 | rs = −0.349 | 17 | 4 | 1 | 1 | rs = −0.707 |
R: Resistance; LS: Low sensitivity; MS: Moderate sensitivity; HS: High sensitivity.