Table 3.
Intention-to-treat analyses (n = 125/130) of effectiveness of a Web-based diabetes-specific depression therapy on symptoms of depression as assessed by a CES-Da score, testing effect modification by depression status, anxiety disorder, or high level of diabetes-specific emotional distress, in a cognitive behavioral therapy (CBT) intervention versus waiting-list (WL) control groupb
| Pretreatment | Post treatment | 1-month follow-up |
P
value |
||||
| CBT | WL | CBT | WL | CBT | WL | ||
| MDDc,d | 30 (7) | 30 (7) | 21 (11) | 24 (9) | 20 (12) | 24 (10) | .49 |
| No MDD | 27 (7) | 26 (7) | 18 (9) | 21 (8) | 19 (10) | 20 (8) | |
| Anxiety disorderd | 32 (7) | 31 (8) | 23 (11) | 25 (9) | 22 (11) | 25 (10) | .71 |
| No anxiety disorder | 27 (7) | 26 (6) | 19 (10) | 21 (8) | 19 (11) | 21 (8) | |
| Elevated diabetes-specific emotional distress (PAID ≥40)e | 31 (7) | 31 (8) | 22 (11) | 24 (9) | 21 (12) | 24 (9) | .92 |
| No elevated diabetes-specific emotional distress (PAID >40)e | 26 (7) | 26 (6) | 18 (10) | 22 (9) | 18 (10) | 21 (9) | |
a Center for Epidemiologic Studies Depression scale.
b Data are given as mean (SD). Statistical tests relied on generalized estimating equation analyses. P values indicate level of significance of effect modification. All analyses are adjusted for baseline CES-D scores, baseline between-group differences on sociodemographic variables, and differences in time between pretreatment and posttreatment. Data are uncorrected.
c Major depressive disorder.
d Diagnosed using the computerized version of the World Health Organization Composite International Diagnostic Interview (WHO CIDI-auto).
e Problem Areas In Diabetes scale.