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Effects of intra-VL PAG microinjections of vehicle (0.05% DMSO in ACSF) or MMPIP (5 μg/0.2 μl) on tail flick latencies (A and B) and the spontaneous firing of RVM OFF (C and D) and ON cells (E) in sham (A and C) and SNI (B, D and E) rats 14 days after surgery. Each point represents the mean ± S.E.M of 12–14 (A and B) or 6–7 (C, D and E) rats per group. * indicates statistically significant difference vs pretreatment values. P values < 0.05 were considered statistically significant.
