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. Author manuscript; available in PMC: 2014 Oct 1.
Published in final edited form as: Transl Stroke Res. 2013 May 31;4(5):10.1007/s12975-013-0265-2. doi: 10.1007/s12975-013-0265-2

Fig. 4.

Fig. 4

P2X7 inhibition stimulates CNTF in the SVZ after stroke. a, b In a cresyl violet-stained coronal section of a C57BL/6 mouse brain, the ischemic injury caused by a unilateral MCAO can be seen in the striatum (STR) and cortex but not the SVZ (arrows). CC corpus callosum, LV lateral ventricle. Scale bar, 250 μm. c The uninjured side is shown for comparison. d MCAO increased CNTF in C57BL/6 mice, while intravenous injections of BBG over 3 days following MCAO increased CNTF mRNA even more in the ipsilateral SVZ as measured by qPCR (n=7 sham, 7 saline MCAO, 8 BBG MCAO). Data are mean ±SEM and calculated as fold of sham-operated control. *=p<0.05, **=p<0.01, ***=p<0.001