Table 1.
Observed V(D)J recombination events
| V-D-J | V-J | D-J | V-D | V-V | t(X;X) | |
|---|---|---|---|---|---|---|
| Sample |
|
|
|
|
|
|
| A) pre-B ALL |
|
(1) IGH* |
|
|
|
|
| (1) IGK | ||||||
| MCL |
|
(2) IGL |
(1) IGH |
|
|
|
| RAMOS |
|
(1) IGK |
(1) IGH |
|
|
|
| B) chronic T-Cell leukemia |
|
(1) TRB |
|
|
|
|
| DB |
|
|
|
|
(1) IGH |
t(14;18) |
| ARH-77 |
|
|
|
|
(1) IGH |
|
| C) LCL |
|
(2) IGK |
(5) IGH |
(1) IGH |
(1) IGH |
|
|
(1) IGK | ||||||
| Loucy |
(2) TRB |
|
|
(1) IGH |
|
|
| Burkitt-like lymphoma | (1) IGK | t(2;8) |
(A) Samples for which only canonical V-D-J recombination was observed. *The V-J rearrangement observed in the pre-B ALL is likely to be normal V-D-J, however we obtained full read alignments only for read pairs mapping one end to IGHJ4 and the other to IGHV4-34. (B) Samples for which only non-canonical events were observed. Non-canonical events are indicated as italicized text. (C) Samples for which both canonical and non-canonical events were observed.