Figure 3. Clomipramine ameliorated anhedonia and psychomotor instability associated with chronic social defeat stress.

(A) All groups preferred 5% sucrose to water, but preference was significantly higher in the Naïve group compared to the Sub+Sal group. Normal sucrose preference was restored in the Sub+Clo group. (B) In the unstressed Naïve Group, locomotor activities were stable. Stress induced an unstable fluctuation in locomotor activity in both Sub+Sal and Sub+Clo groups, but the Sub+Clo group exhibited locomotor activity levels similar to the Naïve group by the recovery phase. *p<0.05.