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. Author manuscript; available in PMC: 2014 Nov 1.
Published in final edited form as: Clin Gastroenterol Hepatol. 2013 May 20;11(11):10.1016/j.cgh.2013.04.050. doi: 10.1016/j.cgh.2013.04.050

Table 3.

Multivariable logistic regression to predict severe-complicated C. difficile infection in hospitalized patients (n=1446).

Variable Odds Ratio 95% Confidence Interval p-value
Peripheral WBC count1 2.2 1.7–2.9 <0.0001
Serum creatinine rise2 1.6 1.3–2.1 <0.0001
Age, per 10 years3 1.1 1.0–1.1 0.0029
Narcotic use4 2.1 1.5–3.0 <0.0001
H2Blocker/PPI4 1.8 1.3–2.6 0.0002
1

Peripheral white blood cell (WBC) count was dichotomized in ≥15 × 109/L and <15 × 109/L

2

Increase in serum creatinine 1.5 fold or more from baseline was compared to an increase <1.5-fold from baseline

3

Age was treated as a continuous variable and studied in 10 year intervals

4

Medication use was examined 7 days prior to and 30 days after C. difficile infection diagnosis