Table 1. Calculated half-life (t1/2) and rate constant (k) for Δ12-PGJ3 #.
Incubated temperatures | |||
Samples | 4°C | 25°C | 37°C |
Gastric juice | 13.1 h [1.47E-05] | 7 h [2.76E-05] | 5.5 h [3.52E-05] |
Intestinal (−Pancreatin) | 9.7 h [1.97E-05] | 3.5 h [5.45E-05] | 3.3 h [5.75E-05] |
Intestinal (+Pancreatin) | 5.9 h [3.26E-05] | 1.2 h [8.56E-05] | 1 h [8.9E-05] |
Half-life (t1/2) and Reaction rate constant (k) (indicated in square brackets) were calculated based on Arrhenius equation-first order kinetics for Δ12-PGJ3 at various incubated temperatures and simulated physiological conditions.