Table 1.
Distribution of KIR genes in the Busselton control population and the group of Western Australian women with a history of CIN
|
KIR gene |
Cases |
Controls |
p-valuea |
p-value correctedb |
|---|---|---|---|---|
| n = 147 | n = 187 | |||
|
2DL1 |
144 (98.0%) |
178 (94.2%) |
0.149 |
1 |
|
2DL2 |
67 (45.6%) |
108 (57.1%) |
0.046* |
0.644 |
|
2DL3 |
136 (92.5%) |
170 (89.9%) |
0.531 |
1 |
|
2DL4 |
147 (100%) |
189 (100%) |
1 |
1 |
|
2DL5 |
78 (53.1%) |
100 (52.9%) |
0.978 |
1 |
|
3DL1 |
133 (90.5%) |
177 (93.7%) |
0.382 |
1 |
|
3DL2 |
147 (100%) |
189 (100%) |
1 |
1 |
|
3DL3 |
147 (100%) |
189 (100%) |
1 |
1 |
|
2DS1 |
58 (39.5%) |
76 (40.2%) |
0.978 |
1 |
|
2DS2 |
68 (46.3%) |
109 (57.7%) |
0.049* |
0.686 |
|
2DS3 |
44 (29.9%) |
55 (29.1%) |
0.964 |
1 |
|
2DS4** |
55 (37.4%) |
77 (40.7%) |
0.612 |
1 |
|
2DS5 |
50 (34.0%) |
57 (30.2%) |
0.526 |
1 |
| 3DS1 | 61 (41.5%) | 78 (41.3%) | 0.967 | 1 |
CIN, Cervical intraepithelial neoplasia; KIR, Killer immunoglobulin-like receptor.
aχ2 test with Yates correction was performed; p-values < 0.05 are indicated in bold for χ2 test.
bCorrected p-values were determined by adjusting p-values for multi-gene analysis using Bonferroni’s correction.
*OR = 0.6; 95% CI 0.4 – 0.9.
**2DS4 psuedogenes not counted.