Table 2. Unadjusted and adjusted Cox regression of factors associated with diarrhoea morbidity in the first 6 months.
|
Overall diarrhoea
|
Persistent diarrhoea
|
Acute diarrhoea
|
|||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Events/
|
Unadj HR | p | Adj HR | p | Unadj HR | p | Adj HR | p | Unadj HR | p | Adj HR | p | ||
Child-years
|
(95% CI) | (95% CI) | (95% CI) | (95% CI) | (95% CI) | (95% CI) | ||||||||
Infant feeding practice | ||||||||||||||
Exclusive breastfeeding | 463/1186 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | |||||||
Predominant | 16/18 | 1.43 | 0.049 | 1.38 | 0.080 | 1.51 | 0.278 | 1.37 | 0.407 | 1.40 | 0.097 | 1.38 | 0.122 | |
Breastfeeding | 157/327 | (1.00-2.05) | (0.96-1.97) | (0.71-3.22) | (0.65-2.93) | (0.94-2.11) | (0.92-2.07) | |||||||
Partial breastfeeding | 147/255 | 1.25 | 0.002 | 1.19 | 0.021 | 1.17 | 0.356 | 1.08 | 0.642 | 1.28 | 0.003 | 1.22 | 0.018 | |
(1.09-1.46) | (1.02-1.53) | (0.84-1.61) | (0.78-1.50) | (1.09-1.51) | (1.03-1.44) | |||||||||
Never breastfed | 1.26 | 0.001 | 1.35 | <0.001 | 1.43 | 0.012 | 1.50 | 0.005 | 1.21 | 0.016 | 1.29 | 0.001 | ||
(1.09-1.44) | (1.17-1.53) | (1.08-1.89) | (1.13-2.00) | (1.03-1.41) | (1.10-1.51) | |||||||||
Infant HIV status | ||||||||||||||
HIV non-exposed | 681/1158 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | |||||||
Perinatal infection or | 63/483 | 1.46 | <0.001 | 1.43 | <0.001 | 2.01 | <0.001 | 2.04 | <0.001 | 1.29 | 0.022 | 1.27 | 0.037 | |
unknown timing | (1.21-1.76) | (1.18-1.72) | (1.48-2.94) | (1.44-2.88) | (1.03-1.61) | (1.01-1.58) | ||||||||
Postnatal infection | 16/139 | 1.67 | 0.017 | 1.76 | 0.009 | 1.05 | 0.932 | 1.12 | 0.849 | 1.84 | 0.008 | 1.95 | 0.004 | |
(1.09-2.55) | (1.15-2.69) | (0.33-3.28) | (0.36-3.50) | (1.16-2.90) | (1.23-3.07) | |||||||||
HIV exposed and | 5/54 | 1.67 | 0.123 | 1.45 | 0.271 | 0.88 | 0.900 | 0.82 | 0.849 | 1.88 | 0.074 | 1.60 | 0.186 | |
Uninfected | (0.86-3.22) | (0.75-2.79) | (0.12-6.27) | (0.36-3.49) | (0.94-3.78) | (0.79-3.21) | ||||||||
Unknown status | 18/22 | 0.31 | <0.001 | 0.44 | <0.001 | 0.33 | 0.029 | 0.44 | 0.108 | 0.31 | <0.001 | 0.43 | 0.002 | |
(0.19-0.50) | (0.27-0.69) | (0.12-0.89) | (0.17-1.20) | (0.18-0.53) | (0.25-0.73) | |||||||||
Sex | ||||||||||||||
Male | 409/924 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | |||||||
Female | 374/923 | 0.85 | 0.002 | 0.86 | 0.004 | 0.72 | 0.002 | 0.73 | 0.004 | 0.89 | 0.050 | 0.90 | 0.082 | |
(0.77-0.94) | (0.78-0.96) | (0.58-0.89) | (0.59-0.91) | (0.80-0.99) | (0.81-1.01) | |||||||||
Water Source | ||||||||||||||
Non-Piped | 289/613 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | |||||||
Piped | 486/1216 | 0.70 | <0.001 | 0.77 | <0.001 | 0.83 | 0.101 | 0.91 | 0.466 | 0.67 | <0.001 | 0.73 | <0.001 | |
(0.63-0.77) | (0.69-0.86) | (0.66-1.03) | (0.73-1.15) | (0.59-0.75) | (0.65-0.82) | |||||||||
Unknown | 8/35.8 | 0.04 | 0.001 | 0.15 | 0.056 | - | - | 0.05 | 0.003 | 0.18 | 0.085 | |||
(0.01-0.28) | (0.02-1.05) | (0.01-0.35) | (0.02-1.27) | |||||||||||
Enrolment clinic | ||||||||||||||
Rural/Peri urban | 704/1615 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | |||||||
Urban | 78/250 | 0.47 | <0.001 | 0.52 | <0.001 | 0.42 | <0.001 | 0.43 | <0.001 | 0.48 | <0.001 | 0.55 | <0.001 | |
(0.39-0.56) | (0.43-0.63) | (0.28-0.63) | (0.28-0.65) | (0.39-0.58) | (0.44-0.67) |