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. 2013 Dec 2;8(12):e81307. doi: 10.1371/journal.pone.0081307

Table 2. Unadjusted and adjusted Cox regression of factors associated with diarrhoea morbidity in the first 6 months.


Overall diarrhoea
Persistent diarrhoea
Acute diarrhoea
Events/
Unadj HR p Adj HR p Unadj HR p Adj HR p Unadj HR p Adj HR p
Child-years
(95% CI) (95% CI) (95% CI) (95% CI) (95% CI) (95% CI)
Infant feeding practice
Exclusive breastfeeding 463/1186 1.00 1.00 1.00 1.00 1.00 1.00
Predominant 16/18 1.43 0.049 1.38 0.080 1.51 0.278 1.37 0.407 1.40 0.097 1.38 0.122
Breastfeeding 157/327 (1.00-2.05) (0.96-1.97) (0.71-3.22) (0.65-2.93) (0.94-2.11) (0.92-2.07)
Partial breastfeeding 147/255 1.25 0.002 1.19 0.021 1.17 0.356 1.08 0.642 1.28 0.003 1.22 0.018
(1.09-1.46) (1.02-1.53) (0.84-1.61) (0.78-1.50) (1.09-1.51) (1.03-1.44)
Never breastfed 1.26 0.001 1.35 <0.001 1.43 0.012 1.50 0.005 1.21 0.016 1.29 0.001
(1.09-1.44) (1.17-1.53) (1.08-1.89) (1.13-2.00) (1.03-1.41) (1.10-1.51)
Infant HIV status
HIV non-exposed 681/1158 1.00 1.00 1.00 1.00 1.00 1.00
Perinatal infection or 63/483 1.46 <0.001 1.43 <0.001 2.01 <0.001 2.04 <0.001 1.29 0.022 1.27 0.037
unknown timing (1.21-1.76) (1.18-1.72) (1.48-2.94) (1.44-2.88) (1.03-1.61) (1.01-1.58)
Postnatal infection 16/139 1.67 0.017 1.76 0.009 1.05 0.932 1.12 0.849 1.84 0.008 1.95 0.004
(1.09-2.55) (1.15-2.69) (0.33-3.28) (0.36-3.50) (1.16-2.90) (1.23-3.07)
HIV exposed and 5/54 1.67 0.123 1.45 0.271 0.88 0.900 0.82 0.849 1.88 0.074 1.60 0.186
Uninfected (0.86-3.22) (0.75-2.79) (0.12-6.27) (0.36-3.49) (0.94-3.78) (0.79-3.21)
Unknown status 18/22 0.31 <0.001 0.44 <0.001 0.33 0.029 0.44 0.108 0.31 <0.001 0.43 0.002
(0.19-0.50) (0.27-0.69) (0.12-0.89) (0.17-1.20) (0.18-0.53) (0.25-0.73)
Sex
Male 409/924 1.00 1.00 1.00 1.00 1.00 1.00
Female 374/923 0.85 0.002 0.86 0.004 0.72 0.002 0.73 0.004 0.89 0.050 0.90 0.082
(0.77-0.94) (0.78-0.96) (0.58-0.89) (0.59-0.91) (0.80-0.99) (0.81-1.01)
Water Source
Non-Piped 289/613 1.00 1.00 1.00 1.00 1.00 1.00
Piped 486/1216 0.70 <0.001 0.77 <0.001 0.83 0.101 0.91 0.466 0.67 <0.001 0.73 <0.001
(0.63-0.77) (0.69-0.86) (0.66-1.03) (0.73-1.15) (0.59-0.75) (0.65-0.82)
Unknown 8/35.8 0.04 0.001 0.15 0.056 - - 0.05 0.003 0.18 0.085
(0.01-0.28) (0.02-1.05) (0.01-0.35) (0.02-1.27)
Enrolment clinic
Rural/Peri urban 704/1615 1.00 1.00 1.00 1.00 1.00 1.00
Urban 78/250 0.47 <0.001 0.52 <0.001 0.42 <0.001 0.43 <0.001 0.48 <0.001 0.55 <0.001
(0.39-0.56) (0.43-0.63) (0.28-0.63) (0.28-0.65) (0.39-0.58) (0.44-0.67)