Table 1. Conversion of methyl farnesoate isomers to epoxides by CYP15A1.

Substrate	Epoxide formation*
Methyl (2E,6E)-farnesoate	2.5 ± 0.5
Methyl (2Z,6E)-farnesoate	ND†
Methyl (2E,6Z)-farnesoate	0.3 ± 0.1
Methyl (2Z,6Z)-farnesoate	ND†

^*Epoxidation is expressed in nmol of product per min/nmol of recombinant CYP15A1 (mean ± SD, n = 3). The epoxidation of the different isomers of methyl farnesoate was assayed as described in Materials and Methods.

^†ND, not detectable.