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. 2004 Mar 15;101(12):4024–4029. doi: 10.1073/pnas.0306980101

Table 3. Specificity of insect P450 enzymes towards methyl farnesoate (MF).

P450 Substrate Reaction Product formed Ref.
CYP15A1 (2E, 6E)-MF Epoxidation (10R)-epoxide (10R):(10S) (98:2) This work
CYP4C7 Sesquiterpenoids ω-Hydroxylation (12E)-alcohol 16
CYP9E1 (2Z) > (2E)-MF (1.5:1) Epoxidation 10, 11-epoxide (10R):(10S) (1:1) *
CYP6A1 MF or JH All 4 isomers Epoxidation 6, 7 or 10, 11-epoxide (10S):(10R) (3:1) 24
*

J. F. Andersen, G.C.U., J.F.K., and R.F., unpublished results