Table 3.

Incidence rate and hazard ratios for chronic kidney disease (CKD) in the hepatitis C virus (HCV)-infected and HCV-uninfected control groups younger than 70 years old and without comorbidities at baseline during the 6-year follow-up period (n = 12760)

	Control group (n = 9700)	HCV-infected group	p
	N (%)	(n = 3060) N (%)
No. of CKD	58 (0.6)	56 (1.8)	<0.0001
Mean follow-up (y)	5.96	5.88	0.0001
Total follow-up (person-years)	57770	18004
Incidence ratea	1.00	3.11	<0.0001
Crude HR (95% CI)	1.00 (reference)	3.09 (2.14-4.47)	<0.0001
Adjusted HR (95% CI)b	1.00 (reference)	2.12 (1.44-3.13)	0.0002

Abbreviations: CI confidence interval, HR hazard ratio.

^aPer 1000 person-years.

^bAdjusted for age, gender, geographic region, urbanization level, enrollee category, and number of health care visits in 1 year before study entry.