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. 2013 Oct 12;9(4):326–338. doi: 10.1007/s13181-013-0339-2

Table 2.

Summary of the specific functional domains affected by each of the two lead exposure regimens and the efficacy of succimer chelation in alleviating the dysfunction

Domain of function Mod Pb High Pb
Pb effect? Succ. benefit? Pb effect? Succ. benefit?
Impaired learning ability Yes Yes Yes No
Impaired regulation of arousal and/or negative emotion No NA Yes Yes
 Greater disruption following an error
Attentional dysfunction
 Sustained attention/error reactivity No NA Yes Yes
 Lapses in attention No NA Yes Intermediate
Impaired inhibitory control No NA Yes No
 Impulsivity

Data from Stangle et al. [20]. [Reproduced with permission from Environmental Health Perspectives]

Pb effect? denotes whether a statistically significant effect of lead was detected, Succ. benefit? indicates whether succimer was efficacious at alleviating the lead induced dysfunction, NA not applicable