Fig. 6.

The absence of Sdc1 reduces the amplification of progenitors induced by ΔNβcat. MECs were isolated from five 2.5- to 3-month-old female mice from each of four genotypes produced by a cross of [ΔNβcat]-transgenic and Sdc1^–/– mice (19). This cohort was of mixed-strain background (a BALB/c/FVB backcross). SP cells were separated by flow cytometry, and the results are presented as percent SP cells relative to ΔNβcat^–/–; Sdc1^+/+ mice. The average and SD were generated from three independent sorts.