Table 3.
Day |
Treatment (n = 22) |
Score |
Score change from baseline (%) |
p-value |
||||
---|---|---|---|---|---|---|---|---|
Mean2 | Median | s.d. | Min | Max | Mean (95% CI) | |||
0 |
Cyclosporine A |
79.28 |
80.58 |
12.45 |
52.60 |
98.92 |
- |
- |
Cyclosporine A and prednisolone |
73.90 |
73.12 |
11.83 |
50.75 |
100.00 |
- |
||
3-4 |
Cyclosporine A |
77.43 |
79.03 |
11.42 |
48.50 |
95.02 |
−1.18 (−7.8,5.5) |
0.0008 |
Cyclosporine A and prednisolone |
47.65 |
50.00 |
22.86 |
10.95 |
96.79 |
−36.33 (−48.7,-24.0) |
||
7-8 |
Cyclosporine A |
67.79 |
69.65 |
14.62 |
38.71 |
95.02 |
−13.04 (−22.3,-3.8) |
0.0008 |
Cyclosporine A and prednisolone |
29.21 |
29.50 |
20.46 |
1.99 |
72.04 |
−60.61 (−73.3,-47.9) |
||
10-11 |
Cyclosporine A |
65.81 |
67.99 |
13.47 |
36.56 |
87.06 |
−15.31 (−24.2,-6.5) |
0.0008 |
Cyclosporine A and prednisolone1 |
23.08 |
16.13 |
22.97 |
0.00 |
74.63 |
−68.73 (−82.7,-54.7) |
||
14 ± 1 |
Cyclosporine A |
58.69 |
57.53 |
18.03 |
26.87 |
93.03 |
−24.57 (−34.9,-14.2) |
0.0008 |
Cyclosporine A and prednisolone |
20.37 |
12.90 |
20.22 |
0.00 |
75.62 |
−72.79 (−84.4,-61.1) |
||
17-18 |
Cyclosporine A |
50.45 |
47.54 |
19.71 |
20.40 |
88.56 |
−34.62 (−47.0,-22.3) |
0.0008 |
Cyclosporine A and prednisolone |
19.33 |
10.75 |
19.50 |
0.00 |
70.00 |
−73.57 (−84.9,-62.3) |
||
21-22 |
Cyclosporine A |
48.33 |
47.79 |
20.26 |
16.13 |
88.56 |
−37.00 (−50.1,-23.9) |
0.0128 |
Cyclosporine A and prednisolone |
21.23 |
11.29 |
24.84 |
0.00 |
84.58 |
−70.55 (−85.5,-55.6) |
||
24-25 |
Cyclosporine A |
43.69 |
42.36 |
24.29 |
3.23 |
88.56 |
−42.41 (−58.2,-26.6) |
0.0240 |
Cyclosporine A and prednisolone |
19.90 |
10.75 |
24.42 |
0.00 |
93.03 |
−73.10 (−86.9,-59.3) |
||
28 ± 2 |
Cyclosporine A1 |
43.44 |
43.01 |
25.09 |
3.23 |
89.05 |
−42.36 (−58.2,-26.5) |
0.2160 |
Cyclosporine A and prednisolone | 26.26 | 15.05 | 28.54 | 0.00 | 94.03 | −65.12 (−81.1,-9.1) |
1n = 21; 2arithmetic mean; s.d. standard deviation.