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. 2004 Mar 15;101(12):4180–4185. doi: 10.1073/pnas.0307067101

Fig. 2.

Fig. 2.

Recombinant mapping identifies the Hsp70 subgenomic region in combination with HLA-B*5701 as the most parsimonious susceptibility region to abacavir hypersensitivity. The region carrying the putative susceptibility loci has been mapped to the MHC class III region on chromosome 6p21.3 (1). Typing of genetic markers within the C4A6–MEGT1 interval present on the 57.1 AH was carried out on abacavir-hypersensitive cases (n = 18) and abacavir-tolerant controls (n = 12) recombinant for the 57.1 AH. For each individual, shading indicates presence of the marker carried by the 57.1 AH.