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. 2013 Nov 21;4(11):e930. doi: 10.1038/cddis.2013.456

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Copyright © 2013 Macmillan Publishers Limited

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported License. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-nd/3.0/

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Morphological alterations from ovarian follicle to testis cord. (a) Active stromal cells surround the giant oocytes (Go) and form degenerative compartment (a). Within the degenerative compartment, follicle cells dissociate from the oocytes (b) and acquire mesenchymal morphology (arrow, a). (c) Degeneration of perinucleolar oocytes (primordial follicles) with marked vacuolation and survival cells from the oocyte decomposition (arrowhead). (d) Coexistence of oocyte degeneration and multinucleated giant cells (Mn) that present many peripheral nuclei and annular chromatin. (e) Regeneration of testis cord tissues. Ac, acidic cells with red coloration; Sc, spermatogenic cysts; Sp, spermatogonia; Tc, testis cord-like structure. Scale bars= 20 μm (b, and d) and 50 μm (a, c and e)