Fig. 16.

Effect of Pre-treatment with Yohimbine (l mg/kg i.p.) on the Pure Isolates from Spondias mombin Extract on Novelty-Induced Grooming (NIG) Behaviour in Mice. One-way ANOVA revealed that there is significant difference between various treatment groups; F(7, 33) = 37.85, P < 0.001. Each bar is mean ± S.E.M. (n = 6). Coumaroyl (10 mg/kg i.p.) increased NIG and abolished the effect of yohimbine (1 mg/kg i.p.) in NIG. Quercetin decreased NIG alone and had no effect when pre-treated with yohimbine. Gallic acid (10 mg/kg i.p.) had no effect alone but reversed the effect of yohimbine.* indicates significant difference from control. P < 0.05 (SNK test)