Table 3.
Factors associated with the serum GGT level stratified by the ALDH2 genotype
| |
ALDH2*1/*1 genotype |
ALDH2*2 allele carrier |
||||
|---|---|---|---|---|---|---|
| β | SE | P value | β | SE | P value | |
| Age |
−0.37 |
0.48 |
0.45 |
−0.70 |
0.30 |
0.02 |
| Diabetes duration |
−0.75 |
0.72 |
0.30 |
−1.38 |
0.57 |
0.02 |
| BMI |
0.52 |
1.39 |
0.71 |
1.80 |
0.87 |
0.04 |
| Systolic BP |
−0.22 |
0.30 |
0.94 |
0.29 |
0.14 |
0.046 |
| Diastolic BP |
0.50 |
0.47 |
0.30 |
0.62 |
0.24 |
0.01 |
| Triglycerides |
0.22 |
0.03 |
< 0.01 |
0.07 |
0.03 |
0.02 |
| AST |
1.48 |
0.24 |
< 0.01 |
0.97 |
0.18 |
< 0.01 |
| ALT |
0.85 |
0.16 |
< 0.01 |
0.56 |
0.10 |
< 0.01 |
| Hypertension |
1.10 |
11.33 |
0.92 |
13.34 |
6.12 |
0.03 |
| Ever smokers |
13.23 |
11.46 |
0.25 |
16.48 |
6.09 |
< 0.01 |
| Drinkers |
26.07 |
11.68 |
0.03 |
8.79 |
6.80 |
0.20 |
| HbA1c | 4.23 | 2.64 | 0.11 | 1.15 | 1.52 | 0.45 |
GGT, γ-glutamyltransferase; ALDH2, aldehyde dehydrogenase 2; SE, standard error; BMI, body mass index; BP, blood pressure; AST, aspartate aminotransferase; ALT, alanine aminotransferase; HbA1c, hemoglobin A1c.