Table 4.
Frozen and permanent section analyses of different patient subgroups
| Type of analysis | N | sensitivity | 95% CI | specificity | 95% CI | PPV | 95% CI | NPV | 95% CI | p-value |
|---|---|---|---|---|---|---|---|---|---|---|
| FS sum |
300 |
68.8 |
53.6-80.9 |
100 |
98.1-100 |
100 |
87.0-100 |
94.4 |
90.7-96.7 |
<0.0001 |
| PS sum |
300 |
89.6 |
76.6-96.1 |
100 |
98.1-100 |
100 |
89.8-100 |
98.1 |
95.3-99.3 |
<0.0001 |
| FS, fnac (+) |
138 |
70.7 |
54.3-83.4 |
100 |
95.3-100 |
100 |
85.4-100 |
89.0 |
81.2-93.9 |
<0.0001 |
| PS, fnac (+) |
138 |
90.2 |
75.9-96.8 |
100 |
95.3-100 |
100 |
88.3-100 |
96.0 |
89.6-98.7 |
<0.0001 |
| FS, fnac (−) |
162 |
57.1 |
20.2-88.2 |
100 |
97.0-100 |
100 |
39.6-100 |
98.1 |
94.1-99.5 |
<0.0001 |
| PS, fnac (−) | 162 | 85.7 | 42.0-99.2 | 100 | 97.0-100 | 100 | 51.7-100 | 99.4 | 95.9-100 | <0.0001 |
FS frozen section, PS permanent section, sum summary analysis, fnac (+), conclusive pre-operative fine-needle aspiration cytology, fnac (−) inconclusive fine-needle aspiration cytology, CI confidence interval, PPV positive predictive value, NPV negative predictive value.