Table 3.
Change of Cys C and GFR after EECP treatment (n = 30)
|
Characteristics |
Median (IQR) |
||
|---|---|---|---|
|
Baseline |
End of 35th session |
Follow-up |
|
| Estimated GFR | |||
| GFR <60 mL/min/1.73 m2 (n = 12) |
n = 12 |
n = 9 |
n = 12 |
| Cystatin C (mg/L) |
1.55 |
1.44 |
1.4 |
| |
(1.26-1.85) |
(1.2-1.59) |
(1.14-1.65) |
|
p-value |
|
0.173 a |
0.004 b ** |
| GFR (mL/min per 1.73 m2) |
43.59 |
46.11 |
47.52 |
| |
(39.1-53.29) |
(42.06-47.26) |
(41.1-55.76) |
|
p-value |
|
0.374 a |
0.003 b ** |
| GFR ≥60 mL/min/1.73 m2 (n = 18) |
n = 18 |
n = 18 |
n = 18 |
| Cystatin C (mg/L) |
0.83 |
0.82 |
0.8 |
| |
(0.73-0.89) |
(0.72-0.91) |
(0.63-0.92) |
|
p-value |
|
0.931 a |
0.052 b |
| GFR (mL/min per 1.73 m2) |
86.05 |
92.34 |
88.81 |
| |
(75.16-103.3) |
(83.46-105.38) |
(81.22-109.79) |
|
p-value |
|
0.157 a |
0.124 b |
|
NT-proBNP |
|
|
|
| NT-proBNP ≤125 pg/mL (n = 9) |
n = 9 |
n = 9 |
n = 9 |
| Cystatin C (mg/L) |
0.78 |
0.82 |
0.81 |
| |
(0.76-0.87) |
(0.72-0.87) |
(0.77-0.87) |
|
p-value |
|
0.906 a |
0.553 b |
| GFR (mL/min per 1.73 m2) |
86.69 |
88.75 |
83.11 |
| |
(85.28-92.84) |
(83.46-105.23) |
(81.42-96.54) |
|
p-value |
|
0.374 a |
0.767 b |
| NT-proBNP >125 pg/mL (n = 20) |
n = 20 |
n = 17 |
n = 20 |
| Cystatin C (mg/L) |
1.26 |
1.16 |
1.14 |
| |
(0.94-1.68) |
(0.84-1.53) |
(0.88-1.51) |
|
p-value |
|
0.523 a |
0.001 b** |
| GFR (mL/min per 1.73 m2) |
59.43 |
57.66 |
62.26 |
| |
(43.31-74.47) |
(46.11-91.46) |
(46.97-83.18) |
|
p-value |
|
0.246 a |
0.001 b** |
|
NT-proBNP decline >30% from baseline (n = 10 ) |
n = 10 |
n = 9 |
n = 10 |
| Cystatin C (mg/L) |
1.01 |
1.00 |
0.97 |
| |
(0.81-1.31) |
(0.77-1.2) |
(0.69-1.2) |
|
p-value |
|
0.594 a |
0.017 b* |
| GFR (mL/min per 1.73 m2) |
65.53 |
66.87 |
66.46 |
| |
(43.68-79.98) |
(47.26-93.98) |
(49.02-91.85) |
| p-value | 0.214 a | 0.051 b | |
Values are Median (25th-75th percentile). p- value was calculated with the use of Wilcoxon signed ranks test, a End of 35th session versus baseline; b Last follow-up versus baseline.
(*) indicated statistically significant p-value less than 0.05; (**) indicated statistically significant p-value less than 0.01.