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. 2013 Aug 9;13:27. doi: 10.1186/1471-2342-13-27

Table 1.

Comparison of lesion conspicuity between filtered back projections and iterative reconstructions

  Standard-dose CT with FBP Low-dose CT with FBP Low-dose CT with ASIR Low-dose CT with MBIR
Consolidation or mass
4.9 ± 0.2
4.7 ± 0.6
4.8 ± 0.4
4.9 ± 0.2
Ground-glass attenuation
5.0 ± 0.2
4.8 ± 0.4
4.8 ± 0.4
4.8 ± 0.4
Reticular opacity
5.0 ± 0
4.9 ± 0.4
5.0 ± 0
5.0 ± 0
Decreased lung attenuation (bulla, emphysema, or cyst)
4.9 ± 0.2
4.5 ± 0.6 *§
4.6 ± 0.5 *§
4.9 ± 0.2
Mediastinal lymph node enlargement 4.8 ± 0.4 3.0 ± 0.5 *§ 4.0 ± 0.5 *§ 4.7 ± 0.5

CT Computed tomography, FBP Filtered back projection, ASIR Adaptive statistical iterative reconstruction, MBIR Model-based iterative reconstruction.

The comparisons of lesion conspicuity scores were made by the Wilcoxon signed-rank test. * refers to statistically significant differences with standard-dose FBP CT (* p < 0.05). § refers to statistically significant differences with low-dose MBIR CT (§ p < 0.05).