Table 1.
Body weight gains after 84 days of continuous oral treatment of fRG in HFD-fed mice.
| Groups | Body weights (g): | Body weight gains during (g): | ||
|---|---|---|---|---|
| At start of administration | At a termination | Adapt period (7 days) | Administration period (84 days) | |
| ND | 27.54 ± 0.88 | 33.01 ± 2.28 | 2.04 ± 0.63 | 5.48 ± 1.58 |
| HFD | 31.04 ± 2.12 a | 50.20 ± 10.44 a | 5.63 ± 1.36 a | 19.16 ± 11.02 a |
| +Simvastatin | 30.40 ± 1.90 a | 39.70 ± 3.28 a,c | 4.51 ± 0.93 a | 9.33 ± 2.82 b,c |
| +Silymarin | 30.24 ± 0.94 a | 44.61 ± 7.88 a | 5.38 ± 1.14 a | 14.38 ± 7.53 a |
| +Metformin | 30.41 ± 1.71 a | 39.31 ± 4.81 ac | 5.09 ± 1.25 a | 8.90 ± 4.36 c |
| +RG 250 mg/kg | 30.29 ± 1.22 a | 44.54 ± 9.23 a | 4.54 ± 0.76 a | 14.25 ± 8.33 b |
| +fRG 500 mg/kg | 30.19 ± 1.19 a | 39.28 ± 9.48 | 4.84 ± 0.86 a | 9.09 ± 9.27 |
| +fRG 250 mg/kg | 30.30 ± 1.11 a | 44.31 ± 5.81 a | 4.58 ± 1.16 a | 14.01 ± 5.66 a |
| +fRG 125 mg/kg | 30.58 ± 1.29 a | 42.56 ± 7.83 a | 4.94 ± 1.00 a | 11.99 ± 8.86 |
Values were expressed mean ± S.D. of eight mice (Significant as compared with ND-fed mice, a p < 0.01; b p < 0.05; significant as compared with HFD-fed mice; c p < 0.05; RG, Red Ginseng; fRG, Red-koji fermented RG; HFD, high fat diet).