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. Author manuscript; available in PMC: 2014 Nov 1.
Published in final edited form as: J Mol Cell Cardiol. 2013 Aug 31;64:10.1016/j.yjmcc.2013.08.006. doi: 10.1016/j.yjmcc.2013.08.006

Figure 6.

Figure 6

Residue-specific mutation of the phosphorylation sites leads to decreased survival probability and conduction abnormalities. A) Kaplan-Meier curve of the different TG lines. NTG, WT and ADA were indistinguishable (n=8–11). B) Representative surface ECG recordings of TG mice showed irregular RR and QT intervals in DAA/(t/t) and AAD/(t/t) hearts. C) Quantitation of the RR intervals (n=6–8). D) Quantitation of QT intervals (n=6–8). Data are expressed as mean ± SD. *P<0.05, versus WT/(t/t), †P <0.0001 versus WT/(t/t).