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. 2013 Dec 3;4:275. doi: 10.3389/fgene.2013.00275

Table 1.

miRNAs silenced by DNA methylation in lung cancer.

miRNA Target genes Reference
mir-9-3 Lujambio etal. (2008), Kitano etal. (2011), and Heller etal. (2012)
mir-34a, -34b/c Bcl-2, Cyclin D1, Cyclin E2, CDK4, CDK6, c-Myc, c-Met Lodygin etal. (2008), Lujambio etal. (2008), Gallardo etal. (2009), Wang etal. (2011), Tanaka etal. (2012), and Watanabe etal. (2012)
mir-124-1, -124-2, -124-3 CDK6 Lujambio etal. (2007) and Kitano etal. (2011)
mir-126 Crk, VEGF-A Watanabe etal. (2012)
mir-148a TGIF2 Lujambio etal. (2008) and Chen etal. (2013)
mir-193a Heller etal. (2012)
mir-200, -205 ZEB1, ZEB2 Tellez etal. (2011)
mir-487b SUZ12, BMI1, WNT5A, MYC, K-ras Xi etal. (2013)