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Incidence of most common adverse reactions (incidence at least 2% higher than placebo) associated with dimethyl fumarate 240 mg twice daily in placebo-controlled trials (studies 1 and 2)1
| Adverse reactions | Dimethyl fumarate (n = 769) | Placebo (n = 771) |
| Flushing | 40% | 6% |
| Abdominal pain | 18% | 10% |
| Diarrhea | 14% | 11% |
| Nausea | 12% | 9% |
| Vomiting | 9% | 5% |
| Pruritus | 8% | 4% |
| Rash | 8% | 3% |
| Albumin urine present | 6% | 4% |
| Dyspepsia | 5% | 3% |
| Erythema | 5% | 1% |
| AST increased | 4% | 2% |
| Lymphopenia | 2% | <1% |
