. 2013 Sep 17;48(8):650–655. doi: 10.1310/hpj4808-650

Table 1.

Summary of therapeutic options in the management of cannabinoid hyperemesis syndrome

Agent	Indication and dosing	Clinical outcome
IV Sodium chloride 0.9%	Hydration 1-2 L bolus and then 150-200 mL/h infusion for 24 to 48 hours	Demonstrated symptom improvement in case reports^4,18

Morphine	Pain 4 mg IV as needed	Demonstrated pain control in case reports¹⁸

Acetaminophen	Headache 650 mg as needed	Demonstrated headache relief in case reports¹⁸

Lorazepam	Nausea/vomiting 1 mg IV x 1 OR 1 mg IV every 4 h as needed	Demonstrated symptom improvement in case reports^18,19

Chlorpromazine	Hiccups 25 mg IV every 4 h as needed	Demonstrated symptom improvement in case reports¹⁸

Note: CHS = cannabinoid hyperemesis syndrome; h = hour; IV = intravenous.