| Proposed Clinical Diagnostic Criteria forCannabinoid Hyperemesis Syndrome12 |
| Essential for diagnosis |
| Long-term cannabis use: more than 1 year |
| Major features |
| Severe cyclic nausea and vomiting |
| Resolution with cannabis cessation |
| Relief of symptoms with hot showers or baths |
| Epigastric or periumbilical abdominal pain |
| Weekly use |
| Supportive features |
| Age younger than 50 years |
| Weight loss over 5 kg |
| Morning predominance of symptoms |
| Normal bowel habits |
| Negative laboratory, radiographic, and endoscopic test results |
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