Table 2.
Wild-type mice (LU5)1 | TSLPR−/− mice (LU5) | |||
---|---|---|---|---|
4T1-12B target cells | YAC-1 target cells4 | 4T1-12B target cells | YAC-1 target cells | |
Control mice2 | ND3 | 2.6 ± 0.3 | ND | 3.1 ± 0.1 |
Day 7 p.i. | ND | 0.4 ± 0.2 | ND | ND |
Day 21 p.i. | ND | 0.9 ± 0.9 | ND | 1.1 ± 0.6 |
Day 35 p.i. | ND | 0.8 ± 0.7 | ND | 0.3 ± 0.3 |
Lytic units were calculated according to the exponential fit as described in the Materials and Methods.
Age- and sex-matched WT or TSLPR−/− mice that had not been injected with tumor cells.
ND: LU5 not determined as percent lysis values were too low.
Positive control cell line.