Table 1.

Shows a summary of the experiment including conditioning regimen, amount of bone marrow received, as well as the immunological response to donor.

	Conditioning regimen received	Total number of Bone marrow cells/Kg recipient weight	Duration of detectable peripheral chimerism	Increase in anti-non-Gal IgG levels	Increase in anti-non-Gal IgM levels	Bone marrow Chimerism at day 28	Invitro cellular response by MLR to GalT-KO pig PBMC after stopping immunosupression.
B156	Basic	1 × 10^ 9	Minutes	No	No	Detected	Not Tested
B158	Basic	7.5 × 10^ 8	Minutes	No	No	Detected	Specific hyporesponse to donor
B270	Basic	1.6 × 10 ^ 9	Minutes	Yes	No	Not detectable	Proliferation to GalT-KO pig donor
B265	Enhanced	4.56 × 10 ^ 9	2 days	Yes	No	Not detectable	Proliferation to GalT-KO pig donor
B284	Enhanced	5.3 × 10^9	4 days	Yes	Yes	Not detectable	Proliferation to GalT-KO pig donor

Basic conditioning regimen: Total Body Irradiation (150 cGy), Thymic irradiation (700 cGy), 2 doses of loCD2b (4mg/kg/dose), 1 dose of Rabbit ATG (20 mg/kg/dose), Splenectomy and continuous tacrolimus to day 28.

Enhanced Conditioning regimen: [Total Body Irradiation (150cGy), Thymic irradiation, (700cGy) 2 doses of loCD2b (4mg/kg/dose), 2 doses of Horse ATG (50 mg/kg/dose), Splenectomy,] plus Rituximab (20 mg/kg/dose), Velcade (1.3mg/kg/m2 BSA), 1 hour Immuno-adsorption and continuous tacrolimus to day 28.