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. 2013 Jul-Sep;5(3):84–91.

Fig. 2.

Fig. 2

Effects of GK-2 on the retention of the skill of finding the submerged platform in the Morris water maze setup, which is deficient in rats with experimental AD induced by the injection of streptozotocin into the cerebral ventricles. The data are presented as medians and interquartile ranges. * – p = 0.017 in comparison to the “sham surgery” group; # – p = 0.012 (“surgery + GK-2”) and 0.014 (“surgery + memantine”) in comparison with the “surgery” group (oneway ANOVA with subsequent post hoc Fisher test). The therapeutic effect (Te) of dipeptide GK-2 was calculated using the following equation: Te= [(c–d)/(e–d)] X 100%, where c is the EL in the “surgery + treatment” group, d is the EL in the “surgery” group, and e is the EL in the “sham surgery” group