Table 1. Determination of effervescent components based on ratio of effervescent materials (Mean ± SD).
| Code | Citric Acid (mg) | Tartaric Acid(mg) | Sodium bicarbonate(mg) | Effervescent time (s) | *Solubility | pH |
| P1 | 85.9 | 171.8 | 292.2 | 55± 2.08 | 2 | 5.35± 0.01 |
| P2 | 85.9 | 85.9 | 292.2 | 50± 3.21 | 3 | 6.30± 0.1 |
| P3 | 85.9 | 128.8 | 292.2 | 67± 1.53 | 2 | 6.11± 0.07 |
| P4 | 85.9 | 257.7 | 292.2 | 73± 3.51 | 1 | 3.51± 0.05 |
| P5 | 85.9 | 343.6 | 292.2 | 75± 1.83 | 1 | 2.72± 0.04 |
| P6 | 171.8 | 171.8 | 292.2 | 67± 2.87 | 2 | 3.45± 0.06 |
| P7 | 42.9 | 85.9 | 292.2 | 53± 1.52 | 3 | 6.74± 0.04 |
| P8 | 64.4 | 85.9 | 292.2 | 60± 2.31 | 3 | 6.47± 0.03 |
| P9 | 128.8 | 85.9 | 292.2 | 67± 1 | 3 | 6.13± 0.02 |
| P10 | 171.8 | 85.9 | 292.2 | 80± 2.08 | 3 | 5.37± 0.08 |
| P11 | - | 85.9 | 292.2 | 68± 2.52 | 2 | 6.48± 0.1 |
| P12 | 85.9 | - | 292.2 | 75± 1.15 | 5 | 6.57± 0.05 |
| P13 | 171.8 | - | 292.2 | 77± 2 | 5 | 6.10± 0.02 |
| P14 | 128.8 | - | 292.2 | 58± 1.53 | 5 | 6.42± 0.05 |
| P15 | 128.8 | - | 146.1 | 60± 2.50 | 5 | 5.59± 0.07 |
| P16 | 128.8 | - | 219.2 | 67± 1.53 | 5 | 6.23± 0.09 |
| P17 | 128.8 | - | 438.3 | 65± 2.31 | 3 | 6.73± 0.04 |
| P18 | 128.8 | - | 584.4 | 65± 3.64 | 3 | 6.75± 0.06 |
| *Solubility of formulations using a standard table15 (1=insoluble; 2=slightly soluble; 3=sparingly soluble; 4=soluble; 5=freely soluble) | ||||||