Table 1. Median, mean, mode, and range for vancomycin MIC's according to year and site of infection by E-test Micro- and Macro-methods.
| Micro-Method (μg/mL) | Macro-Method (μg/mL) | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| N (%) | Median (IQR)a | Mean (95% CI)b | Mode | Range | Median (IQR)a | Mean (95% CI)b | Mode | Range | |
| Year | P = 0.245c | P = 0.052c | |||||||
| 2004 | 12 (16.9) | 1.5 (1.5-1.5) | 1.5 (1.4-1.6) | 1.5 | 1.5-2 | 5.0 (4-6) | 5.3 (3.8-6.9) | 6.0 | 3-12 |
| 2005 | 22 (31.0) | 1.5 (1.5-1.5) | 1.3 (1.2-1.5) | 1.5 | 1-1.5 | 4.0 4-4) | 3.9 (3.3-4.4) | 4.0 | 3-8 |
| 2006 | 12 (16.9) | 1.5 (1-1.5) | 1.4 (1.2-1.5) | 1.5 | 1-1.5 | 3.5 (3-4) | 3.5 (3.2-3.8) | 3.0 | 3-4 |
| 2007 | 15 (21.1) | 1.5 (1.5-1.5) | 1.4 (1.3-1.5) | 1.5 | 1-1.5 | 4.0 (3-4) | 3.9 (3.4-4.5) | 4.0 | 3-6 |
| 2008 | 10 (14.1) | 1.5 (1.5-1.5) | 1.5 (1.3-1.7) | 1.5 | 1-1.5 | 4.0 (3-4) | 3.6 (3.2-4.0) | 4.0 | 3-4 |
| Site of Infection | P = 0.952c | P = 0.085c | |||||||
| Bone | 7 (9.9) | 1.5 (1-1.5) | 1.4 (1.1-1.6) | 1.5 | 1-1.5 | 3.0 (3-6) | 4.0 (2.7-5.3) | 3.0 | 3-6 |
| Blood | 6 (8.5) | 1.5 (1.5-1.5) | 1.5 (1.5-1.5) | 1.5 | 1.5-1.5 | 4.0 (3.8-6.5) | 4.8 (2.9-6.8) | 4.0 | 3-8 |
| Joint | 47 (66.2) | 1.5 (1.5-1.5) | 1.4 (1.3-1.5) | 1.5 | 1-2 | 4.0 (3-4) | 3.7 (3.5-3.9) | 4.0 | 3-6 |
| CSF | 1 (1.4) | 1.5 (1.5-1.5) | 1.5 (NA) | 1.5 | 1.5-1.5 | 4.0 (4-4) | 4.0 (NA) | 4.0 | 4-4 |
| Pleural Fluid | 6 (8.5) | 1.5 (1-1.6) | 1.4 (1-1.8) | 1.5 | 1-2 | 5.0 (3.8-7.5) | 5.8 (2.4-9.2) | 4.0 | 3-12 |
| Pericardial Fluid | 2 (2.8) | 1.5 (1.5-1.5) | 1.5 (1.5-1.5) | 1.5 | 1.5-1.5 | 3.0 (3-3) | 3.0 (3-3) | 3.0 | 3-3 |
| Visceral abscess | 1 (1.4) | 1.5 (1.5-1.5) | 1.5 (NA) | 1.5 | 1.5-1.5 | 4.0 (4-4) | 4.0 (NA) | 4.0 | 4-4 |
| Deep tissue abscess | 1 (1.4) | 1.5 (1.5-1.5) | 1.5 (NA) | 1.5 | 1.5-1.5 | 6.0 (6-6) | 6.0 (NA) | 6.0 | 6-6 |
|
| |||||||||
| Total | 71 (100) | 1.5 (1.5-1.5) | 1.4 (1.4-1.5) | 1.5 | 1-2 | 4.0 (3-4) | 4.0 (3.7-4.4) | 4.0 | 3-12 |
a
IQR, Inter-Quartile Range
b
95% Confidence Interval
c
Kruskal-Wallis H method