Table 5.
Significant predictors for readmissions within 90 days of index hospitalization
| Risk factor | OR | 95% CI | P |
|---|---|---|---|
| All readmissionsa | |||
| Moderate or severe liver disease | 3.10 | 1.47–6.54 | 0.0029 |
| Number of IP hospitalizations in pre-index (≥2 versus 0)c | 2.90 | 2.21–3.80 | <0.0001 |
| Metastatic solid tumor | 1.69 | 1.01–2.81 | 0.0447 |
| Congestive heart failure | 1.50 | 1.25–1.79 | <0.0001 |
| Plan type (HMO versus comprehensive) | 1.46 | 1.11–1.92 | 0.0072 |
| Renal disease | 1.43 | 1.09–1.89 | 0.0102 |
| Number of IP hospitalizations in pre-index (1 versus 0)c | 1.39 | 1.14–1.69 | 0.0013 |
| Myocardial infarction | 1.31 | 1.00–1.72 | 0.0481 |
| Malignancy | 1.29 | 1.01–1.65 | 0.0394 |
| Number of ED visits in pre-index (≥2 versus 0)c | 1.27 | 1.05–1.53 | 0.0149 |
| Systemic corticosteroidsd | 1.22 | 1.06–1.41 | 0.0072 |
| Diabetes | 1.20 | 1.03–1.41 | 0.0199 |
| Number of ICU days in index hospitalization | 1.04 | 1.00–1.07 | 0.0413 |
| COPD-related readmissionsb | |||
| Number of IP hospitalizations in pre-index (≥2 versus 0)c | 3.92 | 2.95–5.20 | <0.0001 |
| Moderate or severe liver disease | 2.79 | 1.23–6.34 | 0.0143 |
| Metastatic solid tumor | 1.82 | 1.08–3.10 | 0.0258 |
| Plan type (HMO versus comprehensive) | 1.62 | 1.17–2.23 | 0.0034 |
| Number of OP visits in pre-index (≥2 versus 0)c | 1.61 | 1.29–2.01 | <0.0001 |
| Number of IP hospitalizations in pre-index (1 versus 0)c | 1.61 | 1.14–2.26 | 0.0064 |
| Long-acting bronchodilator treatmentd | 1.21 | 1.02–1.45 | 0.0313 |
| Number of ICU days in index hospitalization | 1.04 | 1.00–1.08 | 0.0348 |
Notes:
Defined as all readmissions that occurred during the follow-up period, regardless of diagnosis
defined as a subset of all readmissions, which includes only readmissions where COPD was listed as a primary or secondary diagnosis
required COPD diagnosis in any primary or secondary position
within 90-day period before index hospitalization. Statistically significant odds ratios are reported when corresponding two-sided P-values are ≤0.05 from multivariable stepwise logistic regression analyses.
Abbreviations: CI, confidence interval; COPD, chronic obstructive pulmonary disease; ED, emergency department; HMO, health maintenance organization; ICU, intensive care unit; IP, inpatient; OP, outpatient; OR, odds ratio.