Figure 1.
Effects of BD, EB, DEB, and the DEB-GSH conjugate on mutation (A, B) and survival (C, D) in E. coli TRG8 cells with or without GST/GSH and mouse liver microsomes. Rifampicin resistant mutants were obtained on LB plates containing 100 µg mL−1 rifampicin. The mutation frequency of the rpoB gene was corrected with the number of survivors following the treatment. Each point represents the mean of duplicate experiments.