Figure 2.

Monthly seizure frequency in a TSC girl. A girl with a TSC2 mutation presented refractory seizures since the age of 7 years. When she was 20 years old she presented mainly secondarily generalized tonic and tonic-clonic seizures. The image shows her seizure frequency per month before and during Everolimus treatment. With everolimus seizure frequency decreased, generalized seizures stopped, and she continued to have only focal onset seizures of short duration, without drop attacks nor falling to the ground.