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. 2013 Aug 22;13:131. doi: 10.1186/1471-230X-13-131

Figure 1.

Figure 1

Inter-individual variability of the gut microbiota is greater in Crohn’s disease than healthy controls. (A) Principal coordinates analysis (PCoA) plot based on weighted UniFrac distances between biopsies from Crohn’s and non-IBD patients. Biopsies in Crohn’s patients were taken of inflamed and healthy-appearing mucosa. Biopsies did not cluster by inflammation or location. (B) Average pairwise weighted UniFrac distances (±s.e.m.) among subsets of biopsies. Asterisks indicate significant differences: * P<0.05; ** P<0.005 (Student’s t-test with 1,000 Monte Carlo simulations). Phylum-level classifications of a single (C) ileal or (D) colonic sample from each patient’s initial procedure within this study. The Rutgeerts score at post-operative colonoscopy is denoted below surgical samples from Crohn’s patients. Phyla are sorted from top to bottom in overall decreasing prevalence.