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IC50 values (μM) of the naphthoquinones on the proliferation of T. cruzi epimastigotes
| Cpd | 1 day | 2 days | 3 days | 4 days |
|---|---|---|---|---|
| NQ1 |
0.30 ± 0.08a |
0.24 ± 0.03 |
0.26 ± 0.04 |
0.26 ± 0.05 |
| NQ8 |
0.76 ± 0.12 |
0.35 ± 0.09 |
0.24 ± 0.10 |
0.36 ± 0.07 |
| NQ9 |
2.62 ± 0.38 |
1.05 ± 0.19 |
1.08 ± 0.17 |
1.27 ± 0.21 |
| NQ12 | 0.55 ± 0.01 | 0.48 ± 0.06 | 0.45 ± 0.05 | 0.44 ± 0.11 |
aMean ± standard deviation of at least three independent experiments.
