Figure 2.

Phylogenetic tree derived for VP60 gene nucleotide sequences of 127 rabbit lagoviruses including 7 RHDV2. The tree was obtained using the Neighbor-Joining method and was drawn to a scale of nucleotide substitutions per site. The percentages greater than 70% of replicate trees in which the associated taxa clustered together in the bootstrap test (1000 replicates) are given in italics before each major branch node. The European brown hare syndrome virus (EBHSV) strain GD (Z69620) was used as an outgroup to root the tree. The names of some representative strains from different countries are shown. For RHDV, the genetic groups G1 to G6 according to Le Gall-Reculé et al. [16] and clade 1 to 4, or A to D, according to Kerr et al. [18] or to Kinnear et al. [19], respectively, are annotated.