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. 2013 Sep 23;13:24. doi: 10.1186/1471-2253-13-24

Table 2.

Applied trigger agents and clinical presentations of malignant hyperthermia suspected events

No IVCT Trigger agents Masseterspasm Dantrolene application Cardiac arrhythmia Max. end-tidal CO2[mmHg] Max. temperature Max. Creatine kinase [U/L]
1
MHS
Isoflurane + SCh
Unknown
1 × 200 mg
Sinus tachycardia
48 mmHg
38.8°C
10.514
2
MHS
Isoflurane + SCh
Yes
1 × 240 mg
Tachyarrhythmia
54 mmHg
36.1°C
> 10.000
3
MHS
Sevoflurane + SCh
Yes
No
Sinus tachycardia
Unknown
Unknown
51.557
4
MHS
Sevoflurane + SCh
Unknown
2 × 200 mg
Sinus tachycardia
62 mmHg
Unknown
23.700
5
MHS
Desflurane + SCh
Unknown
1 × 220 mg
Tachyarrhythmia
56 mmHg
37.6°C
≈ 80.000
6
MHS
Sevoflurane
No
1 × 200 mg
No
85 mmHg
37.5°C
38.762
7
MHS
Isoflurane + SCh
Unknown
No
Unknown
Unknown
Unknown
16.412
8
MHEh
SCh
Yes
1 × 200 mg
Unknown
39 mmHg
Unknown
119.150
9
MHEh
SCh
Yes
Unknown
No
36 mmHg
Unknown
162
10
MHEh
SCh
Yes
No
Unknown
Unknown
Unknown
2.234
11
MHEh
Halothane + SCh
Yes
Unknown
Tachyarrhythmia
Unknown
Unknown
Low
12
MHN
SCh
Yes
No
Tachyarrhythmia
Unknown
Unknown
132
13
MHN
Isoflurane
Yes
No
Unknown
54 mmHg
Unknown
4.100
14
MHN
SCh
Yes
No
Unknown
Unknown
Unknown
24.732
15
MHN
Desflurane
No
1 × 180 mg
Tachyarrhythmia
72 mmHg
Unknown
Unknown
16
MHN
SCh
Yes
No
Unknown
Unknown
Unknown
Unknown
17
MHN
Desflurane
No
No
Unknown
Unknown
38,5°C
Unknown
18
MHN
Isoflurane + SCh
Yes
No
Unknown
41 mmHg
Unknown
5.174
19 MHN Enflurane + SCh Yes No Unknown 75 mmHg Unknown 4.820

IVCT In vitro contracture test, MHS Malignant hyperthermia susceptible, MHN malignant hyperthermia non-susceptible, MHEh Malignant hyperthermia equivocal to halothane, SCh Succinylcholine, CO2 Carbon dioxide.