Table 1.
Specific symptoms in women with malignant or benign ovarian tumors and controls (healthy women)
| |
Malignant |
Benign |
Controls |
p-value |
p-value |
p-value |
|||
|---|---|---|---|---|---|---|---|---|---|
| |
tumors |
tumors |
|
|
|
|
|||
|
(n = 60) |
(n = 116) |
(150) |
(Malignant vs. benign) |
(Malignant vs. controls) |
(Benign vs. controls) |
||||
| Symptom | N | (%) | n | (%) | n | (%) | |||
| Pelvic pain |
30 |
(50.0) |
23 |
(19.7) |
2 |
(1.3) |
<0.01 |
<0.01 |
<0.01 |
| Abdominal pain |
23 |
(38.3) |
10 |
(8.5) |
0 |
- |
<0.01 |
<0.01 |
<0.01 |
| Back pain |
17 |
(28.3) |
10 |
(8.6) |
0 |
- |
<0.01 |
<0.01 |
<0.01 |
| Unable to eat normally |
22 |
(36.7) |
8 |
(6.8) |
1 |
(0.7) |
<0.01 |
<0.01 |
0.01 |
| Feeling full quickly |
22 |
(36.1) |
11 |
(9.4) |
1 |
(0.7) |
<0.01 |
<0.01 |
<0.01 |
| Indigestion |
15 |
(24.6) |
7 |
(6.0) |
1 |
(0.7) |
<0.01 |
<0.01 |
0.02 |
| Nausea or vomiting |
11 |
(18.0) |
4 |
(3.4) |
1 |
(0.7) |
<0.01 |
<0.01 |
0.17 |
| Weight loss |
19 |
(31.7) |
25 |
(21.6) |
11 |
(7.3) |
0.19 |
<0.01 |
<0.01 |
| Abdominal bloating |
36 |
(60.0) |
32 |
(27.4) |
0 |
- |
<0.01 |
<0.01 |
<0.01 |
| Increased abdomen size |
38 |
(63.3) |
31 |
(26.7) |
1 |
(0.7) |
<0.01 |
<0.01 |
<0.01 |
| Able to feel abdominal mass |
14 |
(23.3) |
11 |
(9.4) |
0 |
- |
0.02 |
<0.01 |
<0.01 |
| Urinary urgency |
8 |
(13.3) |
8 |
(6.8) |
2 |
(1.3) |
0.25 |
<0.01 |
0.02 |
| Frequent urination |
12 |
(20.0) |
16 |
(13.7) |
2 |
(1.3) |
0.38 |
<0.01 |
<0.01 |
| Constipation |
2 |
(3.3) |
2 |
(1.7) |
0 |
- |
0.60 |
0.08 |
0.18 |
| Diarrhea |
3 |
(5.1) |
1 |
(0.9) |
0 |
- |
0.11 |
0.02 |
0.43 |
| Menstrual irregularities* |
1 |
(1.6) |
1 |
(0.9) |
1 |
(0.7) |
1.0 |
0.49 |
1.0 |
| Bleeding after menopause** |
6 |
(10.0) |
1 |
(0.9) |
0 |
- |
<0.01 |
<0.01 |
0.43 |
| Pain during intercourse*** |
0 |
- |
0 |
- |
1 |
(0.7) |
NC |
1.0 |
1.0 |
| Bleeding with intercourse |
0 |
- |
0 |
- |
0 |
- |
NC |
NC |
NC |
| Fatigue |
20 |
(33.3) |
16 |
(13.7) |
3 |
(2.0) |
<0.01 |
<0.01 |
<0.01 |
| Leg swelling |
6 |
(10.0) |
11 |
(9.4) |
1 |
(0.7) |
1.0 |
<0.01 |
<0.01 |
| Difficulty breathing | 9 | (15.0) | 5 | (4.3) | 2 | (1.3) | 0.02 | <0.01 | 0.24 |
*only for premenopausal women; **only for postmenopausal women; ***only for sexually active women; NC non-computable.
P-value: bivariate pairwise comparisons using chi-squares or the Fisher’s exact test where appropriate.