Table 2.

ACQ score change from baseline to week 13 (ITT population)

Variable	Placebo		Combined MEDI-528		P Valueb
	n	Mean (SD)	n	Mean (SD)
All subjectsa	82	−1.23 (0.95)	245	−1.22 (1.07)	0.86
Asthma typea
Atopic	70	−1.28 (0.97)	206	−1.19 (1.04)	0.55
Non-atopic	12	−0.94 (0.82)	39	−1.42 (1.18)	0.41
ICS usea
Medium dose	43	−1.21 (0.97)	117	−1.17 (1.02)	0.55
High dose	39	−1.26 (0.94)	128	−1.28 (1.11)	0.77
Eosinophil counta
≥ 0.3 × 103/μL	44	−1.39 (0.95)	120	−1.17 (1.01)	0.14
< 0.3 × 103/μL	38	−1.04 (0.92)	124	−1.26 (1.09)	0.22
All subjects without imputation	67	−1.30 (0.94)	208	−1.28 (1.10)	0.75

Abbreviations: ACQ Asthma Control Questionnaire, ICS Inhaled corticosteroid.

^aMissing mean ACQ score at Week 13 was imputed using the last observation carried forward method.

^bP-values are calculated using an analysis of covariance with treatment and baseline value as covariates.