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. 2001 Nov 21;70(1):181–191. doi: 10.1086/338308

Table 1.

Single-Locus Genetic Models

Model q f0 f1 f2 g0 g1 Kmale Kfemale λmm λmf λff Description
Dominant:
 1 .1 0 .5 .5 0 .5 .050 .095 5.5 3.1 4.1 No phenocopies, reduced penetrance
 2 .1 .005 1 1 .005 1 .105 .194 5.1 3.0 4.0 5% of cases are phenocopies, full penetrance
 3 .1 .005 .5 .5 .005 .5 .055 .099 4.7 2.8 3.8 5% of cases are phenocopies, reduced penetrance
 4 .1 .05 .5 .5 .05 .5 .095 .136 2.0 1.6 2.3 Half of cases are phenocopies, reduced penetrance
Additive:
 5 .1 0 .25 .5 0 .5 .050 .050 5.5 3.3 4.4 No phenocopies, reduced penetrance
 6 .1 .005 .5 1 .005 1 .105 .104 5.1 3.0 4.1 5% of cases are phenocopies, full penetrance
 7 .1 .005 .25 .5 .005 .5 .055 .054 4.7 2.9 3.8 5% of cases are phenocopies, reduced penetrance
 8 .1 .05 .25 .5 .05 .5 .095 .091 2.0 1.5 1.7 Half of cases are phenocopies, reduced penetrance
Recessive:
 9 .1 0 0 .5 0 .5 .050 .005 5.5 5.5 55.0 No phenocopies, reduced penetrance
 10 .1 .005 .005 1 .005 1 .105 .015 5.1 3.9 24.9 5% of cases are phenocopies, full penetrance
 11 .1 .005 .005 .5 .005 .5 .055 .010 4.7 3.0 14.4 5% of cases are phenocopies, reduced penetrance
 12 .1 .05 .05 .5 .05 .5 .095 .055 2.0 1.2 1.4 Half of cases are phenocopies, reduced penetrance